PDB 6b70

PDB Information

PDB6B70
MethodELECTRON MICROSCOPY
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Zhang, Z., Liang, W.G., Bailey, L.J., Tan, Y.Z., Wei, H., Wang, A., Farcasanu, M., Woods, V.A., McCord, L.A., Lee, D., Shang, W., Deprez-Poulain, R., Deprez, B., Liu, D.R., Koide, A., Koide, S., Kossiakoff, A.A., Li, S., Carragher, B., Potter, C.S., Tang, W.J.
Elife
HeaderHydrolase/Immune System/Hormone
Released2017-10-03
Resolution3.700
CATH Insert Date07 Jan, 2018

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
a 07 Jan, 2018 Rejected
A 07 Jan, 2018 Chopped
B 07 Jan, 2018 Chopped
c 07 Jan, 2018 Rejected
C 07 Jan, 2018 Chopped
D 07 Jan, 2018 Chopped
E 07 Jan, 2018 Chopped
F 07 Jan, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6b70A01 11 Jan, 2018 3.30.830.10 Assigned
6b70A02 11 Jan, 2018 3.30.830.10 Assigned
6b70A03 11 Jan, 2018 3.30.830.10 Assigned
6b70A04 11 Jan, 2018 3.30.830.10 Assigned
6b70B01 11 Jan, 2018 3.30.830.10 Assigned
6b70B02 11 Jan, 2018 3.30.830.10 Assigned
6b70B03 11 Jan, 2018 3.30.830.10 Assigned
6b70B04 11 Jan, 2018 3.30.830.10 Assigned
6b70C01 11 Jan, 2018 Holding pen
6b70C02 11 Jan, 2018 2.60.40.10 Assigned
6b70D01 23 Mar, 2018 2.60.40.10 Assigned
6b70D02 23 Mar, 2018 2.60.40.10 Assigned
6b70E01 11 Jan, 2018 Holding pen
6b70E02 11 Jan, 2018 2.60.40.10 Assigned
6b70F01 23 Mar, 2018 2.60.40.10 Assigned
6b70F02 23 Mar, 2018 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P01308 INS_HUMAN Homo sapiens Insulin
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P01308 INS_HUMAN Homo sapiens Insulin