PDB 6b3s

PDB Links
Overview

PDB Information

PDB	6B3S
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Molecular Basis for Necitumumab Inhibition of EGFR Variants Associated with Acquired Cetuximab Resistance. Bagchi, A., Haidar, J.N., Eastman, S.W., Vieth, M., Topper, M., Iacolina, M.D., Walker, J.M., Forest, A., Shen, Y., Novosiadly, R.D., Ferguson, K.M. Mol. Cancer Ther.
Header	Transferase/Immune System
Released	2017-09-23
Resolution	2.800
CATH Insert Date	17 Dec, 2017

PDB Images (33)

6b3s

PDB 6b3s

6b3sA

PDB Chain 6b3sA

6b3sB

PDB Chain 6b3sB

6b3sC

PDB Chain 6b3sC

6b3sD

PDB Chain 6b3sD

6b3sE

PDB Chain 6b3sE

6b3sF

PDB Chain 6b3sF

6b3sG

PDB Chain 6b3sG

6b3sH

PDB Chain 6b3sH

6b3sI

PDB Chain 6b3sI

6b3sJ

PDB Chain 6b3sJ

6b3sK

PDB Chain 6b3sK

6b3sL

PDB Chain 6b3sL

6b3sA00

CATH Domain 6b3sA00

6b3sB00

CATH Domain 6b3sB00

6b3sC01

CATH Domain 6b3sC01

6b3sC02

CATH Domain 6b3sC02

6b3sD01

CATH Domain 6b3sD01

6b3sD02

CATH Domain 6b3sD02

6b3sE00

CATH Domain 6b3sE00

6b3sF01

CATH Domain 6b3sF01

6b3sF02

CATH Domain 6b3sF02

6b3sG01

CATH Domain 6b3sG01

6b3sG02

CATH Domain 6b3sG02

6b3sH01

CATH Domain 6b3sH01

6b3sH02

CATH Domain 6b3sH02

6b3sI00

CATH Domain 6b3sI00

6b3sJ01

CATH Domain 6b3sJ01

6b3sJ02

CATH Domain 6b3sJ02

6b3sK01

CATH Domain 6b3sK01

6b3sK02

CATH Domain 6b3sK02

6b3sL01

CATH Domain 6b3sL01

6b3sL02

CATH Domain 6b3sL02

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	17 Dec, 2017	Chopped
B	17 Dec, 2017	Chopped
C	17 Dec, 2017	Chopped
D	17 Dec, 2017	Chopped
E	17 Dec, 2017	Chopped
F	17 Dec, 2017	Chopped
G	17 Dec, 2017	Chopped
H	17 Dec, 2017	Chopped
I	17 Dec, 2017	Chopped
J	17 Dec, 2017	Chopped
K	17 Dec, 2017	Chopped
L	17 Dec, 2017	Chopped

CATH Domains (20)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6b3sA00	23 Dec, 2017	3.80.20.20	Assigned
6b3sB00	23 Dec, 2017	3.80.20.20	Assigned
6b3sC01	23 Dec, 2017		Holding pen
6b3sC02	23 Dec, 2017	2.60.40.10	Assigned
6b3sD01	12 Jul, 2018	2.60.40.10	Assigned
6b3sD02	12 Jul, 2018	2.60.40.10	Assigned
6b3sE00	23 Dec, 2017	3.80.20.20	Assigned
6b3sF01	23 Dec, 2017		Holding pen
6b3sF02	23 Dec, 2017	2.60.40.10	Assigned
6b3sG01	12 Jul, 2018	2.60.40.10	Assigned
6b3sG02	12 Jul, 2018	2.60.40.10	Assigned
6b3sH01	23 Dec, 2017		Holding pen
6b3sH02	23 Dec, 2017	2.60.40.10	Assigned
6b3sI00	23 Dec, 2017	3.80.20.20	Assigned
6b3sJ01	23 Dec, 2017		Holding pen
6b3sJ02	23 Dec, 2017	2.60.40.10	Assigned
6b3sK01	12 Jul, 2018	2.60.40.10	Assigned
6b3sK02	12 Jul, 2018	2.60.40.10	Assigned
6b3sL01	12 Jul, 2018	2.60.40.10	Assigned
6b3sL02	12 Jul, 2018	2.60.40.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P00533	EGFR_HUMAN	Homo sapiens	Epidermal growth factor receptor
P00533	EGFR_HUMAN	Homo sapiens	Epidermal growth factor receptor
P00533	EGFR_HUMAN	Homo sapiens	Epidermal growth factor receptor
P00533	EGFR_HUMAN	Homo sapiens	Epidermal growth factor receptor