×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB 6b3e

PDB Information

PDB6B3E
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-Based Design of Selective Noncovalent CDK12 Inhibitors.
Johannes, J.W., Denz, C.R., Su, N., Wu, A., Impastato, A.C., Mlynarski, S., Varnes, J.G., Prince, D.B., Cidado, J., Gao, N., Haddrick, M., Jones, N.H., Li, S., Li, X., Liu, Y., Nguyen, T.B., O'Connell, N., Rivers, E., Robbins, D.W., Tomlinson, R., Yao, T., Zhu, X., Ferguson, A.D., Lamb, M.L., Manchester, J.I., Guichard, S.
ChemMedChem
HeaderTransferase/Inhibitor
Released2017-09-21
Resolution3.060
CATH Insert Date07 Jan, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2018 Chopped
B 07 Jan, 2018 Chopped
C 07 Jan, 2018 Chopped
D 07 Jan, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6b3eA01 11 Jan, 2018 3.30.200.20 Assigned
6b3eA02 11 Jan, 2018 1.10.510.10 Assigned
6b3eB01 11 Jan, 2018 1.10.472.10 Assigned
6b3eB02 11 Jan, 2018 1.10.472.10 Assigned
6b3eC01 11 Jan, 2018 3.30.200.20 Assigned
6b3eC02 11 Jan, 2018 1.10.510.10 Assigned
6b3eD01 11 Jan, 2018 1.10.472.10 Assigned
6b3eD02 11 Jan, 2018 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O75909 CCNK_HUMAN Homo sapiens Cyclin-K
Q9NYV4 CDK12_HUMAN Homo sapiens Cyclin-dependent kinase 12
O75909 CCNK_HUMAN Homo sapiens Cyclin-K
Q9NYV4 CDK12_HUMAN Homo sapiens Cyclin-dependent kinase 12
CATH-Gene3D is a Global Biodata Core Resource Learn more...