PDB 6b0f

PDB Information

PDB6B0F
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
Tria, G.S., Abrams, T., Baird, J., Burks, H.E., Firestone, B., Gaither, L.A., Hamann, L.G., He, G., Kirby, C.A., Kim, S., Lombardo, F., Macchi, K.J., McDonnell, D.P., Mishina, Y., Norris, J.D., Nunez, J., Springer, C., Sun, Y., Thomsen, N.M., Wang, C., Wang, J., Yu, B., Tiong-Yip, C.L., Peukert, S.
J. Med. Chem.
HeaderHormone Receptor
Released2017-09-14
Resolution2.860
CATH Insert Date03 Jun, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6b0fA00 28 Jun, 2018 1.10.565.10 Assigned
6b0fB00 28 Jun, 2018 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor