PDB Information

PDB6AGT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Baragana, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J.A., Pisco, J.P., Peet, C., Dranow, D.M., Robinson, D.A., Jansen, C., Norcross, N.R., Vinayak, S., Anderson, M., Brooks, C.F., Cooper, C.A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T.E., Hallyburton, I., Horst, B.G., Hulverson, M.A., Ferguson, L., Jimenez-Diaz, M.B., Jumani, R.S., Lorimer, D.D., Love, M.S., Maher, S., Matthews, H., McNamara, C.W., Miller, P., O'Neill, S., Ojo, K.K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L.M., Scullion, P., Sharma, A., Shepherd, S.M., Shishikura, Y., Simeons, F.R.C., Stebbins, E.E., Stojanovski, L., Straschil, U., Tamaki, F.K., Tamjar, J., Torrie, L.S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F.J., Maser, P., Kyle, D.E., Winzeler, E.A., Myler, P.J., Wyatt, P.G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C.D., Gray, D.W., Fairlamb, A.H., Pisliakov, A.V., Walpole, C., Read, K.D., Van Voorhis, W.C., Gilbert, I.H.
Proc. Natl. Acad. Sci. U.S.A.
HeaderLigase/Inhibitor
Released2018-08-14
Resolution1.950
CATH Insert Date17 Mar, 2019

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped
C 17 Mar, 2019 Chopped
D 17 Mar, 2019 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6agtA01 18 Mar, 2019 2.40.50.140 Assigned
6agtA02 18 Mar, 2019 3.30.930.10 Assigned
6agtB01 18 Mar, 2019 2.40.50.140 Assigned
6agtB02 18 Mar, 2019 3.30.930.10 Assigned
6agtC01 18 Mar, 2019 2.40.50.140 Assigned
6agtC02 18 Mar, 2019 3.30.930.10 Assigned
6agtD01 18 Mar, 2019 2.40.50.140 Assigned
6agtD02 18 Mar, 2019 3.30.930.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q8IDJ8 Q8IDJ8_PLAF7 Plasmodium falciparum 3D7 Lysine--tRNA ligase
Q8IDJ8 Q8IDJ8_PLAF7 Plasmodium falciparum 3D7 Lysine--tRNA ligase
Q8IDJ8 Q8IDJ8_PLAF7 Plasmodium falciparum 3D7 Lysine--tRNA ligase
Q8IDJ8 Q8IDJ8_PLAF7 Plasmodium falciparum 3D7 Lysine--tRNA ligase