PDB 6aak

PDB Information

PDB6AAK
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor
Hamaguchi, H., Amano, Y., Moritomo, A., Shirakami, S., Nakajima, Y., Nakai, K., Nomura, N., Ito, M., Higashi, Y., Inoue, T.
Bioorg. Med. Chem.
HeaderTransferase/Inhibitor
Released2018-07-18
Resolution2.670
CATH Insert Date19 Aug, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 19 Aug, 2018 Chopped
B 19 Aug, 2018 Chopped
C 19 Aug, 2018 Chopped
D 19 Aug, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6aakA01 20 Aug, 2018 3.30.200.20 Assigned
6aakA02 20 Aug, 2018 1.10.510.10 Assigned
6aakB01 20 Aug, 2018 3.30.200.20 Assigned
6aakB02 20 Aug, 2018 1.10.510.10 Assigned
6aakC01 20 Aug, 2018 3.30.200.20 Assigned
6aakC02 20 Aug, 2018 1.10.510.10 Assigned
6aakD01 20 Aug, 2018 3.30.200.20 Assigned
6aakD02 20 Aug, 2018 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3