PDB 6aak

PDB Links
Overview

PDB Information

PDB	6AAK
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor Hamaguchi, H., Amano, Y., Moritomo, A., Shirakami, S., Nakajima, Y., Nakai, K., Nomura, N., Ito, M., Higashi, Y., Inoue, T. Bioorg. Med. Chem.
Header	Transferase/Inhibitor
Released	2018-07-18
Resolution	2.670
CATH Insert Date	19 Aug, 2018

PDB Images (13)

Image of CATH 6aak

6aak

PDB 6aak

Image of CATH 6aakA

6aakA

PDB Chain 6aakA

Image of CATH 6aakB

6aakB

PDB Chain 6aakB

Image of CATH 6aakC

6aakC

PDB Chain 6aakC

Image of CATH 6aakD

6aakD

PDB Chain 6aakD

Image of CATH 6aakA01

6aakA01

CATH Domain 6aakA01

Image of CATH 6aakA02

6aakA02

CATH Domain 6aakA02

Image of CATH 6aakB01

6aakB01

CATH Domain 6aakB01

Image of CATH 6aakB02

6aakB02

CATH Domain 6aakB02

Image of CATH 6aakC01

6aakC01

CATH Domain 6aakC01

Image of CATH 6aakC02

6aakC02

CATH Domain 6aakC02

Image of CATH 6aakD01

6aakD01

CATH Domain 6aakD01

Image of CATH 6aakD02

6aakD02

CATH Domain 6aakD02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	19 Aug, 2018	Chopped
B	19 Aug, 2018	Chopped
C	19 Aug, 2018	Chopped
D	19 Aug, 2018	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6aakA01	20 Aug, 2018	3.30.200.20	Assigned
6aakA02	20 Aug, 2018	1.10.510.10	Assigned
6aakB01	20 Aug, 2018	3.30.200.20	Assigned
6aakB02	20 Aug, 2018	1.10.510.10	Assigned
6aakC01	20 Aug, 2018	3.30.200.20	Assigned
6aakC02	20 Aug, 2018	1.10.510.10	Assigned
6aakD01	20 Aug, 2018	3.30.200.20	Assigned
6aakD02	20 Aug, 2018	1.10.510.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P52333	JAK3_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK3
P52333	JAK3_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK3
P52333	JAK3_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK3
P52333	JAK3_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK3