PDB Information

PDB5YXH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.
Mahoney, S.J., Narayan, S., Molz, L., Berstler, L.A., Kang, S.A., Vlasuk, G.P., Saiah, E.
Nat Commun
HeaderSignaling Protein
Released2017-12-05
Resolution2.040
CATH Insert Date03 Jun, 2018

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5yxhA00 28 Jun, 2018 3.40.50.300 Assigned
5yxhB00 28 Jun, 2018 3.40.50.300 Assigned
5yxhC00 28 Jun, 2018 3.40.50.300 Assigned
5yxhD00 28 Jun, 2018 3.40.50.300 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15382 RHEB_HUMAN Homo sapiens GTP-binding protein Rheb
Q15382 RHEB_HUMAN Homo sapiens GTP-binding protein Rheb
Q15382 RHEB_HUMAN Homo sapiens GTP-binding protein Rheb
Q15382 RHEB_HUMAN Homo sapiens GTP-binding protein Rheb