PDB 5xxh

PDB Information

PDB5XXH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer.
Xiang, Q., Wang, C., Zhang, Y., Xue, X., Song, M., Zhang, C., Li, C., Wu, C., Li, K., Hui, X., Zhou, Y., Smaill, J.B., Patterson, A.V., Wu, D., Ding, K., Xu, Y.
Eur J Med Chem
HeaderTransferase
Released2017-07-04
Resolution1.620
CATH Insert Date06 Jul, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5xxhA00 19 Jul, 2018 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q92793 CBP_HUMAN Homo sapiens CREB-binding protein
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