PDB Information

PDB5XS2
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Discovery of potent and selective CDK8 inhibitors through FBDD approach
Han, X., Jiang, M., Zhou, C., Zhou, Z., Xu, Z., Wang, L., Mayweg, A.V., Niu, R., Jin, T.G., Yang, S.
Bioorg. Med. Chem. Lett.
HeaderTransferase
Released2017-06-12
Resolution2.040
CATH Insert Date14 Nov, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5xs2A01 10 Dec, 2017 3.30.200.20 Assigned
5xs2A02 10 Dec, 2017 1.10.510.10 Assigned
5xs2B01 10 Dec, 2017 1.10.472.10 Assigned
5xs2B02 10 Dec, 2017 1.10.472.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P24863 CCNC_HUMAN Homo sapiens Cyclin-C
P49336 CDK8_HUMAN Homo sapiens Cyclin-dependent kinase 8