PDB Information

PDB5X69
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
Chen, D., Jansson, A., Sim, D., Larsson, A., Nordlund, P.
J. Biol. Chem.
HeaderTransferase
Released2017-02-21
Resolution2.690
CATH Insert Date14 Nov, 2017

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5x69A00 10 Dec, 2017 3.30.572.10 Assigned
5x69B00 10 Dec, 2017 3.30.572.10 Assigned
5x69C00 10 Dec, 2017 3.30.572.10 Assigned
5x69D00 10 Dec, 2017 3.30.572.10 Assigned
5x69E00 10 Dec, 2017 3.30.572.10 Assigned
5x69F00 10 Dec, 2017 3.30.572.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase