PDB 5x5a
PDB Information
| PDB | 5X5A |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem.
|
| Header | Transferase |
| Released | 2017-02-15 |
| Resolution | 2.390 |
| CATH Insert Date | 14 Nov, 2017 |
PDB Images (13)
5x5a
PDB 5x5a
5x5aA
PDB Chain 5x5aA
5x5aB
PDB Chain 5x5aB
5x5aC
PDB Chain 5x5aC
5x5aD
PDB Chain 5x5aD
5x5aE
PDB Chain 5x5aE
5x5aF
PDB Chain 5x5aF
5x5aA00
CATH Domain 5x5aA00
5x5aB00
CATH Domain 5x5aB00
5x5aC00
CATH Domain 5x5aC00
5x5aD00
CATH Domain 5x5aD00
5x5aE00
CATH Domain 5x5aE00
5x5aF00
CATH Domain 5x5aF00
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 14 Nov, 2017 | Chopped |
| B | 14 Nov, 2017 | Chopped |
| C | 14 Nov, 2017 | Chopped |
| D | 14 Nov, 2017 | Chopped |
| E | 14 Nov, 2017 | Chopped |
| F | 14 Nov, 2017 | Chopped |
CATH Domains (6)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5x5aA00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x5aB00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x5aC00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x5aD00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x5aE00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x5aF00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
UniProtKB Entries (6)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |