PDB 5x1v

PDB Information

PDB5X1V
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator
Matsui, Y., Yasumatsu, I., Asahi, T., Kitamura, T., Kanai, K., Ubukata, O., Hayasaka, H., Takaishi, S., Hanzawa, H., Katakura, S.
Bioorg. Med. Chem.
HeaderTransferase
Released2017-01-27
Resolution2.100
CATH Insert Date14 Nov, 2017

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5x1vA01 10 Dec, 2017 3.40.1380.20 Assigned
5x1vA02 10 Dec, 2017 3.20.20.60 Assigned
5x1vA03 10 Dec, 2017 Holding pen
5x1vB01 10 Dec, 2017 3.40.1380.20 Assigned
5x1vB02 10 Dec, 2017 3.20.20.60 Assigned
5x1vB03 10 Dec, 2017 Holding pen
5x1vC01 10 Dec, 2017 3.40.1380.20 Assigned
5x1vC02 10 Dec, 2017 3.20.20.60 Assigned
5x1vC03 10 Dec, 2017 Holding pen
5x1vD01 10 Dec, 2017 3.40.1380.20 Assigned
5x1vD02 10 Dec, 2017 3.20.20.60 Assigned
5x1vD03 10 Dec, 2017 Holding pen

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM