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PDB Information

PDB5WDY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models.
Yamada, K., Levell, J., Yoon, T., Kohls, D., Yowe, D., Rigel, D.F., Imase, H., Yuan, J., Yasoshima, K., DiPetrillo, K., Monovich, L., Xu, L., Zhu, M., Kato, M., Jain, M., Idamakanti, N., Taslimi, P., Kawanami, T., Argikar, U.A., Kunjathoor, V., Xie, X., Yagi, Y.I., Iwaki, Y., Robinson, Z., Park, H.M.
J. Med. Chem.
HeaderTransferase
Released2017-07-06
Resolution2.460
CATH Insert Date14 Nov, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5wdyA01 05 Apr, 2018 3.30.200.20 Assigned
5wdyA02 05 Apr, 2018 1.10.510.10 Assigned
5wdyB01 05 Apr, 2018 3.30.200.20 Assigned
5wdyB02 05 Apr, 2018 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9H4A3 WNK1_HUMAN Homo sapiens Serine/threonine-protein kinase WNK1
Q9H4A3 WNK1_HUMAN Homo sapiens Serine/threonine-protein kinase WNK1
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