PDB Information

PDB5W6E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Potent and Selective Periphery-Restricted Quinazoline Inhibitors of the Cyclic Nucleotide Phosphodiesterase PDE1.
Humphrey, J.M., Movsesian, M., Am Ende, C.W., Becker, S.L., Chappie, T.A., Jenkinson, S., Liras, J.L., Liras, S., Orozco, C., Pandit, J., Vajdos, F.F., Vandeput, F., Yang, E., Menniti, F.S.
J. Med. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2017-06-16
Resolution1.900
CATH Insert Date06 Jul, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5w6eA00 19 Jul, 2018 1.10.1300.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q01064 PDE1B_HUMAN Homo sapiens Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B