PDB 5w5j

PDB Information

PDB5W5J
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
He, X., Da Ros, S., Nelson, J., Zhu, X., Jiang, T., Okram, B., Jiang, S., Michellys, P.Y., Iskandar, M., Espinola, S., Jia, Y., Bursulaya, B., Kreusch, A., Gao, M.Y., Spraggon, G., Baaten, J., Clemmer, L., Meeusen, S., Huang, D., Hill, R., Nguyen-Tran, V., Fathman, J., Liu, B., Tuntland, T., Gordon, P., Hollenbeck, T., Ng, K., Shi, J., Bordone, L., Liu, H.
ACS Med Chem Lett
HeaderHydrolase/Hydrolase Inhibitor
Released2017-06-15
Resolution2.850
CATH Insert Date14 Nov, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5w5jA00 16 Dec, 2017 1.10.510.10 Assigned
5w5jB00 16 Dec, 2017 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O43353 RIPK2_HUMAN Homo sapiens Receptor-interacting serine/threonine-protein kinase 2
O43353 RIPK2_HUMAN Homo sapiens Receptor-interacting serine/threonine-protein kinase 2