PDB Information

PDB5W0Q
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).
Romero, F.A., Murray, J., Lai, K.W., Tsui, V., Albrecht, B.K., An, L., Beresini, M.H., de Leon Boenig, G., Bronner, S.M., Chan, E.W., Chen, K.X., Chen, Z., Choo, E.F., Clagg, K., Clark, K., Crawford, T.D., Cyr, P., de Almeida Nagata, D., Gascoigne, K.E., Grogan, J.L., Hatzivassiliou, G., Huang, W., Hunsaker, T.L., Kaufman, S., Koenig, S.G., Li, R., Li, Y., Liang, X., Liao, J., Liu, W., Ly, J., Maher, J., Masui, C., Merchant, M., Ran, Y., Taylor, A.M., Wai, J., Wang, F., Wei, X., Yu, D., Zhu, B.Y., Zhu, X., Magnuson, S.
J. Med. Chem.
HeaderTranscription Regulator/Inhibitor
Released2017-05-31
Resolution1.700
CATH Insert Date03 Jun, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5w0qA00 28 Jun, 2018 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q92793 CBP_HUMAN Homo sapiens CREB-binding protein