PDB Information

PDB5VX2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Brouwer, J.M., Lan, P., Cowan, A.D., Bernardini, J.P., Birkinshaw, R.W., van Delft, M.F., Sleebs, B.E., Robin, A.Y., Wardak, A., Tan, I.K., Reljic, B., Lee, E.F., Fairlie, W.D., Call, M.J., Smith, B.J., Dewson, G., Lessene, G., Colman, P.M., Czabotar, P.E.
Mol. Cell
HeaderApoptosis
Released2017-05-23
Resolution1.850
CATH Insert Date17 Dec, 2017

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped
B 17 Dec, 2017 Rejected
C 17 Dec, 2017 Chopped
D 17 Dec, 2017 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5vx2A01 23 Dec, 2017 1.10.437.10 Assigned
5vx2C01 23 Dec, 2017 1.10.437.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P97287 MCL1_MOUSE Mus musculus Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
P97287 MCL1_MOUSE Mus musculus Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1