PDB 5vqm

PDB Information

PDB5VQM
MethodX-RAY DIFFRACTION
Host OrganismBacillus megaterium
Gene SourcePeptoclostridium difficile
Primary Citation
A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells.
Kroh, H.K., Chandrasekaran, R., Zhang, Z., Rosenthal, K., Woods, R., Jin, X., Nyborg, A.C., Rainey, G.J., Warrener, P., Melnyk, R.A., Spiller, B.W., Lacy, D.B.
J. Biol. Chem.
HeaderToxin/Immune System
Released2017-05-09
Resolution2.790
CATH Insert Date17 Dec, 2017

PDB Images (21)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped
B 17 Dec, 2017 Chopped
C 17 Dec, 2017 Chopped
D 17 Dec, 2017 Chopped
H 17 Dec, 2017 Chopped
L 17 Dec, 2017 Chopped

CATH Domains (14)

Domain ID Date inserted into CATH Superfamily CATH Status
5vqmA01 22 Dec, 2017 1.20.58.1190 Assigned
5vqmA02 22 Dec, 2017 Holding pen
5vqmA03 22 Dec, 2017 1.10.10.1780 Assigned
5vqmB01 22 Dec, 2017 1.20.58.1190 Assigned
5vqmB02 22 Dec, 2017 Holding pen
5vqmB03 22 Dec, 2017 1.10.10.1780 Assigned
5vqmC01 23 Mar, 2018 2.60.40.10 Assigned
5vqmC02 23 Mar, 2018 2.60.40.10 Assigned
5vqmD01 22 Dec, 2017 Holding pen
5vqmD02 22 Dec, 2017 2.60.40.10 Assigned
5vqmH01 22 Dec, 2017 Holding pen
5vqmH02 22 Dec, 2017 2.60.40.10 Assigned
5vqmL01 23 Mar, 2018 2.60.40.10 Assigned
5vqmL02 23 Mar, 2018 2.60.40.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
C9YJ35 C9YJ35_PEPDR Clostridioides difficile R20291 Toxin B
S6B291 S6B291_HUMAN Homo sapiens IgG H chain
Q8TCD0 Q8TCD0_HUMAN Homo sapiens Uncharacterized protein
Q8TCD0 Q8TCD0_HUMAN Homo sapiens Uncharacterized protein
S6B291 S6B291_HUMAN Homo sapiens IgG H chain
C9YJ35 C9YJ35_PEPDR Clostridioides difficile R20291 Toxin B