PDB 5v8v

PDB Information

PDB5V8V
MethodX-RAY DIFFRACTION
Host OrganismBaculoviridae
Gene SourceHomo sapiens
Primary Citation
Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition.
Lawhorn, B.G., Tran, T., Hong, V.S., Morgan, L.A., Le, B.T., Harpel, M.R., Jolivette, L., Diaz, E., Schwartz, B., Gross, J.W., Tomaszek, T., Semus, S., Concha, N., Smallwood, A., Holt, D.A., Kallander, L.S.
Bioorg. Med. Chem. Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2017-03-22
Resolution2.600
CATH Insert Date14 Nov, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5v8vA01 10 Dec, 2017 2.40.70.10 Assigned
5v8vA02 10 Dec, 2017 2.40.70.10 Assigned
5v8vB01 10 Dec, 2017 2.40.70.10 Assigned
5v8vB02 10 Dec, 2017 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin
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