PDB 5v4l

PDB Information

PDB5V4L
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli 'BL21-Gold(DE3)pLysS AG'
Gene SourceCryptococcus neoformans
Primary Citation
Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
Chitty, J.L., Blake, K.L., Blundell, R.D., Koh, Y.Q.A.E., Thompson, M., Robertson, A.A.B., Butler, M.S., Cooper, M.A., Kappler, U., Williams, S.J., Kobe, B., Fraser, J.A.
J. Biol. Chem.
HeaderLyase
Released2017-03-09
Resolution2.100
CATH Insert Date14 Nov, 2017

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5v4lA01 10 Dec, 2017 1.10.275.10 Assigned
5v4lA02 10 Dec, 2017 1.20.200.10 Assigned
5v4lA03 10 Dec, 2017 6.10.250.1570 Assigned
5v4lB01 10 Dec, 2017 1.10.275.10 Assigned
5v4lB02 10 Dec, 2017 1.20.200.10 Assigned
5v4lB03 10 Dec, 2017 6.10.250.1570 Assigned
5v4lC01 10 Dec, 2017 1.10.275.10 Assigned
5v4lC02 10 Dec, 2017 1.20.200.10 Assigned
5v4lC03 10 Dec, 2017 6.10.250.1570 Assigned
5v4lD01 10 Dec, 2017 1.10.275.10 Assigned
5v4lD02 10 Dec, 2017 1.20.200.10 Assigned
5v4lD03 10 Dec, 2017 6.10.250.1570 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
J9VSX1 J9VSX1_CRYNH Cryptococcus neoformans var. grubii H99 Adenylosuccinate lyase
J9VSX1 J9VSX1_CRYNH Cryptococcus neoformans var. grubii H99 Adenylosuccinate lyase
J9VSX1 J9VSX1_CRYNH Cryptococcus neoformans var. grubii H99 Adenylosuccinate lyase
J9VSX1 J9VSX1_CRYNH Cryptococcus neoformans var. grubii H99 Adenylosuccinate lyase