PDB 5v49

PDB Links
Overview

PDB Information

PDB	5V49
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Trypanosoma brucei brucei
Primary Citation	Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors. Huang, W., Zhang, Z., Ranade, R.M., Gillespie, J.R., Barros-Alvarez, X., Creason, S.A., Shibata, S., Verlinde, C.L.M.J., Hol, W.G.J., Buckner, F.S., Fan, E. Bioorg. Med. Chem. Lett.
Header	Ligase/Ligase Inhibitor
Released	2017-03-08
Resolution	2.300
CATH Insert Date	14 Nov, 2017

PDB Images (9)

Image of CATH 5v49

5v49

PDB 5v49

Image of CATH 5v49A

5v49A

PDB Chain 5v49A

Image of CATH 5v49B

5v49B

PDB Chain 5v49B

Image of CATH 5v49A01

5v49A01

CATH Domain 5v49A01

Image of CATH 5v49A02

5v49A02

CATH Domain 5v49A02

Image of CATH 5v49A03

5v49A03

CATH Domain 5v49A03

Image of CATH 5v49B01

5v49B01

CATH Domain 5v49B01

Image of CATH 5v49B02

5v49B02

CATH Domain 5v49B02

Image of CATH 5v49B03

5v49B03

CATH Domain 5v49B03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5v49A01	10 Dec, 2017	3.40.50.620	Assigned
5v49A02	10 Dec, 2017	2.170.220.10	Assigned
5v49A03	10 Dec, 2017	1.10.730.10	Assigned
5v49B01	10 Dec, 2017	3.40.50.620	Assigned
5v49B02	10 Dec, 2017	2.170.220.10	Assigned
5v49B03	10 Dec, 2017	1.10.730.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q38C91	Q38C91_TRYB2	Trypanosoma brucei brucei TREU927	Methionyl-tRNA synthetase, putative
Q38C91	Q38C91_TRYB2	Trypanosoma brucei brucei TREU927	Methionyl-tRNA synthetase, putative