PDB 5v0n

PDB Information

PDB5V0N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1'-P2' ligands.
Ghosh, A.K., Brindisi, M., Yen, Y.C., Cardenas, E.L., Ella-Menye, J.R., Kumaragurubaran, N., Huang, X., Tang, J., Mesecar, A.D.
Bioorg. Med. Chem. Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2017-02-28
Resolution2.160
CATH Insert Date14 May, 2017

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 15 May, 2017 Chopped
B 15 May, 2017 Chopped
C 15 May, 2017 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5v0nA01 06 Nov, 2017 2.40.70.10 Assigned
5v0nA02 06 Nov, 2017 2.40.70.10 Assigned
5v0nB01 06 Nov, 2017 2.40.70.10 Assigned
5v0nB02 06 Nov, 2017 2.40.70.10 Assigned
5v0nC01 06 Nov, 2017 2.40.70.10 Assigned
5v0nC02 06 Nov, 2017 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1