PDB 5uwf

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Overview

PDB Information

PDB	5UWF
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties. Dyck, B., Branstetter, B., Gharbaoui, T., Hudson, A.R., Breitenbucher, J.G., Gomez, L., Botrous, I., Marrone, T., Barido, R., Allerston, C.K., Cedervall, E.P., Xu, R., Sridhar, V., Barker, R., Aertgeerts, K., Schmelzer, K., Neul, D., Lee, D., Massari, M.E., Andersen, C.B., Sebring, K., Zhou, X., Petroski, R., Limberis, J., Augustin, M., Chun, L.E., Edwards, T.E., Peters, M., Tabatabaei, A. J. Med. Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2017-02-21
Resolution	1.870
CATH Insert Date	07 May, 2017

PDB Images (5)

Image of CATH 5uwf

5uwf

PDB 5uwf

Image of CATH 5uwfC

5uwfC

PDB Chain 5uwfC

Image of CATH 5uwfD

5uwfD

PDB Chain 5uwfD

Image of CATH 5uwfC00

5uwfC00

CATH Domain 5uwfC00

Image of CATH 5uwfD00

5uwfD00

CATH Domain 5uwfD00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
C	08 May, 2017	Chopped
D	08 May, 2017	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5uwfC00	25 May, 2017	1.10.1300.10	Assigned
5uwfD00	26 May, 2017	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A