PDB Information

PDB5UVF
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations.
Counago, R.M., Allerston, C.K., Savitsky, P., Azevedo, H., Godoi, P.H., Wells, C.I., Mascarello, A., de Souza Gama, F.H., Massirer, K.B., Zuercher, W.J., Guimaraes, C.R.W., Gileadi, O.
Sci Rep
HeaderTransferase/Transferase Inhibitor
Released2017-02-20
Resolution2.000
CATH Insert Date07 May, 2017

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5uvfA01 26 May, 2017 Holding pen
5uvfA02 26 May, 2017 1.10.510.10 Assigned
5uvfB01 26 May, 2017 Holding pen
5uvfB02 26 May, 2017 1.10.510.10 Assigned
5uvfC01 26 May, 2017 Holding pen
5uvfC02 26 May, 2017 1.10.510.10 Assigned
5uvfD01 25 May, 2017 Holding pen
5uvfD02 25 May, 2017 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q99986 VRK1_HUMAN Homo sapiens Serine/threonine-protein kinase VRK1
Q99986 VRK1_HUMAN Homo sapiens Serine/threonine-protein kinase VRK1
Q99986 VRK1_HUMAN Homo sapiens Serine/threonine-protein kinase VRK1
Q99986 VRK1_HUMAN Homo sapiens Serine/threonine-protein kinase VRK1