PDB 5uv5

PDB Information

PDB5UV5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 group M subtype B (isolate BH10)
Primary Citation
A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase.
Kirby, K.A., Myshakina, N.A., Christen, M.T., Chen, Y.L., Schmidt, H.A., Huber, A.D., Xi, Z., Kim, S., Rao, R.K., Kramer, S.T., Yang, Q., Singh, K., Parniak, M.A., Wang, Z., Ishima, R., Sarafianos, S.G.
Antimicrob. Agents Chemother.
HeaderTransferase/Transferase Inhibitor
Released2017-02-19
Resolution3.000
CATH Insert Date14 Nov, 2017

PDB Images (23)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped

CATH Domains (18)

Domain ID Date inserted into CATH Superfamily CATH Status
5uv5A01 10 Dec, 2017 3.10.10.10 Assigned
5uv5A02 10 Dec, 2017 3.30.70.270 Assigned
5uv5A03 10 Dec, 2017 3.30.70.270 Assigned
5uv5A04 10 Dec, 2017 3.30.70.270 Assigned
5uv5A05 10 Dec, 2017 3.30.420.10 Assigned
5uv5B01 10 Dec, 2017 3.10.10.10 Assigned
5uv5B02 10 Dec, 2017 3.30.70.270 Assigned
5uv5B03 10 Dec, 2017 3.30.70.270 Assigned
5uv5B04 10 Dec, 2017 3.30.70.270 Assigned
5uv5C01 10 Dec, 2017 3.10.10.10 Assigned
5uv5C02 10 Dec, 2017 3.30.70.270 Assigned
5uv5C03 10 Dec, 2017 3.30.70.270 Assigned
5uv5C04 10 Dec, 2017 3.30.70.270 Assigned
5uv5C05 10 Dec, 2017 3.30.420.10 Assigned
5uv5D01 10 Dec, 2017 3.10.10.10 Assigned
5uv5D02 10 Dec, 2017 3.30.70.270 Assigned
5uv5D03 10 Dec, 2017 3.30.70.270 Assigned
5uv5D04 10 Dec, 2017 3.30.70.270 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein