PDB Information

PDB5UQV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
USP7 small-molecule inhibitors interfere with ubiquitin binding.
Kategaya, L., Di Lello, P., Rouge, L., Pastor, R., Clark, K.R., Drummond, J., Kleinheinz, T., Lin, E., Upton, J.P., Prakash, S., Heideker, J., McCleland, M., Ritorto, M.S., Alessi, D.R., Trost, M., Bainbridge, T.W., Kwok, M.C.M., Ma, T.P., Stiffler, Z., Brasher, B., Tang, Y., Jaishankar, P., Hearn, B.R., Renslo, A.R., Arkin, M.R., Cohen, F., Yu, K., Peale, F., Gnad, F., Chang, M.T., Klijn, C., Blackwood, E., Martin, S.E., Forrest, W.F., Ernst, J.A., Ndubaku, C., Wang, X., Beresini, M.H., Tsui, V., Schwerdtfeger, C., Blake, R.A., Murray, J., Maurer, T., Wertz, I.E.
Nature
HeaderHydrolase/Hydrolase Inhibitor
Released2017-02-08
Resolution2.840
CATH Insert Date14 Nov, 2017

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5uqvA01 05 Apr, 2018 Holding pen
5uqvA02 05 Apr, 2018 2.20.210.10 Assigned
5uqvA03 05 Apr, 2018 Holding pen
5uqvB01 05 Apr, 2018 Holding pen
5uqvB02 05 Apr, 2018 2.20.210.10 Assigned
5uqvB03 05 Apr, 2018 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q93009 UBP7_HUMAN Homo sapiens Ubiquitin carboxyl-terminal hydrolase 7
Q93009 UBP7_HUMAN Homo sapiens Ubiquitin carboxyl-terminal hydrolase 7