PDB 5upz

PDB Information

PDB5UPZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex.
Ghosh, A.K., Brindisi, M., Nyalapatla, P.R., Takayama, J., Ella-Menye, J.R., Yashchuk, S., Agniswamy, J., Wang, Y.F., Aoki, M., Amano, M., Weber, I.T., Mitsuya, H.
Bioorg. Med. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2017-02-05
Resolution1.270
CATH Insert Date14 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 May, 2017 Chopped
B 15 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5upzA00 06 Nov, 2017 2.40.70.10 Assigned
5upzB00 06 Nov, 2017 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
CATH-Gene3D is a Global Biodata Core Resource Learn more...