PDB 5uob

PDB Information

PDB5UOB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.
Cinelli, M.A., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2017-01-31
Resolution2.290
CATH Insert Date14 May, 2017

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 15 May, 2017 Chopped
B 15 May, 2017 Chopped
C 15 May, 2017 Chopped
D 15 May, 2017 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5uobA01 06 Nov, 2017 3.90.340.10 Assigned
5uobA02 06 Nov, 2017 3.90.440.10 Assigned
5uobA03 06 Nov, 2017 3.90.1230.10 Assigned
5uobB01 06 Nov, 2017 3.90.340.10 Assigned
5uobB02 06 Nov, 2017 3.90.440.10 Assigned
5uobB03 06 Nov, 2017 3.90.1230.10 Assigned
5uobC01 06 Nov, 2017 3.90.340.10 Assigned
5uobC02 06 Nov, 2017 3.90.440.10 Assigned
5uobC03 06 Nov, 2017 3.90.1230.10 Assigned
5uobD01 06 Nov, 2017 3.90.340.10 Assigned
5uobD02 06 Nov, 2017 3.90.440.10 Assigned
5uobD03 06 Nov, 2017 3.90.1230.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial