×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB 5uo8

PDB Information

PDB5UO8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.
Cinelli, M.A., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2017-01-31
Resolution2.180
CATH Insert Date14 May, 2017

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 15 May, 2017 Chopped
B 15 May, 2017 Chopped
C 15 May, 2017 Chopped
D 15 May, 2017 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5uo8A01 06 Nov, 2017 3.90.340.10 Assigned
5uo8A02 06 Nov, 2017 3.90.440.10 Assigned
5uo8A03 06 Nov, 2017 3.90.1230.10 Assigned
5uo8B01 06 Nov, 2017 3.90.340.10 Assigned
5uo8B02 06 Nov, 2017 3.90.440.10 Assigned
5uo8B03 06 Nov, 2017 3.90.1230.10 Assigned
5uo8C01 06 Nov, 2017 3.90.340.10 Assigned
5uo8C02 06 Nov, 2017 3.90.440.10 Assigned
5uo8C03 06 Nov, 2017 3.90.1230.10 Assigned
5uo8D01 06 Nov, 2017 3.90.340.10 Assigned
5uo8D02 06 Nov, 2017 3.90.440.10 Assigned
5uo8D03 06 Nov, 2017 3.90.1230.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
CATH-Gene3D is a Global Biodata Core Resource Learn more...