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PDB Information
| PDB | 5UO4 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21(DE3) |
| Gene Source | Homo sapiens |
| Primary Citation |
Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.
Cinelli, M.A., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
|
| Header | Oxidoreductase/Oxidoreductase Inhibitor |
| Released | 2017-01-31 |
| Resolution | 2.000 |
| CATH Insert Date | 14 May, 2017 |
PDB Images (9)
5uo4A01
CATH Domain 5uo4A01
5uo4A02
CATH Domain 5uo4A02
5uo4A03
CATH Domain 5uo4A03
5uo4B01
CATH Domain 5uo4B01
5uo4B02
CATH Domain 5uo4B02
5uo4B03
CATH Domain 5uo4B03
PDB Chains (2)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 15 May, 2017 | Chopped
|
| B | 15 May, 2017 | Chopped
|
CATH Domains (6)
UniProtKB Entries (2)
| Accession |
Gene ID |
Taxon |
Description |
| P29475 |
NOS1_HUMAN |
Homo sapiens |
Nitric oxide synthase, brain |
| P29475 |
NOS1_HUMAN |
Homo sapiens |
Nitric oxide synthase, brain |