PDB 5ula

PDB Information

PDB5ULA
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice.
Cheung, K., Lu, G., Sharma, R., Vincek, A., Zhang, R., Plotnikov, A.N., Zhang, F., Zhang, Q., Ju, Y., Hu, Y., Zhao, L., Han, X., Meslamani, J., Xu, F., Jaganathan, A., Shen, T., Zhu, H., Rusinova, E., Zeng, L., Zhou, J., Yang, J., Peng, L., Ohlmeyer, M., Walsh, M.J., Zhang, D.Y., Xiong, H., Zhou, M.M.
Proc. Natl. Acad. Sci. U.S.A.
HeaderTranscription/Inhibitor
Released2017-01-24
Resolution1.500
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ulaA01 25 May, 2017 1.20.920.10 Assigned
5ulaB01 25 May, 2017 1.20.920.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4