PDB Information

PDB5UFJ
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin.
Metcalf, B., Chuang, C., Dufu, K., Patel, M.P., Silva-Garcia, A., Johnson, C., Lu, Q., Partridge, J.R., Patskovska, L., Patskovsky, Y., Almo, S.C., Jacobson, M.P., Hua, L., Xu, Q., Gwaltney, S.L., Yee, C., Harris, J., Morgan, B.P., James, J., Xu, D., Hutchaleelaha, A., Paulvannan, K., Oksenberg, D., Li, Z.
ACS Med Chem Lett
HeaderOxygen Transport
Released2017-01-04
Resolution2.050
CATH Insert Date07 May, 2017

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5ufjA00 24 May, 2017 Check for nw result
5ufjB00 24 May, 2017 Check for nw result
5ufjC00 24 May, 2017 Check for nw result
5ufjD00 24 May, 2017 Check for nw result

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P69905 HBA_HUMAN Homo sapiens Hemoglobin subunit alpha
P69905 HBA_HUMAN Homo sapiens Hemoglobin subunit alpha
P68871 HBB_HUMAN Homo sapiens Hemoglobin subunit beta
P68871 HBB_HUMAN Homo sapiens Hemoglobin subunit beta