PDB 5ufj

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Overview

PDB Information

PDB	5UFJ
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. Metcalf, B., Chuang, C., Dufu, K., Patel, M.P., Silva-Garcia, A., Johnson, C., Lu, Q., Partridge, J.R., Patskovska, L., Patskovsky, Y., Almo, S.C., Jacobson, M.P., Hua, L., Xu, Q., Gwaltney, S.L., Yee, C., Harris, J., Morgan, B.P., James, J., Xu, D., Hutchaleelaha, A., Paulvannan, K., Oksenberg, D., Li, Z. ACS Med Chem Lett
Header	Oxygen Transport
Released	2017-01-04
Resolution	2.050
CATH Insert Date	07 May, 2017

PDB Images (9)

Image of CATH 5ufj

5ufj

PDB 5ufj

Image of CATH 5ufjA

5ufjA

PDB Chain 5ufjA

Image of CATH 5ufjB

5ufjB

PDB Chain 5ufjB

Image of CATH 5ufjC

5ufjC

PDB Chain 5ufjC

Image of CATH 5ufjD

5ufjD

PDB Chain 5ufjD

Image of CATH 5ufjA00

5ufjA00

CATH Domain 5ufjA00

Image of CATH 5ufjB00

5ufjB00

CATH Domain 5ufjB00

Image of CATH 5ufjC00

5ufjC00

CATH Domain 5ufjC00

Image of CATH 5ufjD00

5ufjD00

CATH Domain 5ufjD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped
C	08 May, 2017	Chopped
D	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5ufjA00	24 May, 2017	1.10.490.10	Assigned
5ufjB00	24 May, 2017	1.10.490.10	Assigned
5ufjC00	24 May, 2017	1.10.490.10	Assigned
5ufjD00	24 May, 2017	1.10.490.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P68871	HBB_HUMAN	Homo sapiens	Hemoglobin subunit beta
P69905	HBA_HUMAN	Homo sapiens	Hemoglobin subunit alpha
P69905	HBA_HUMAN	Homo sapiens	Hemoglobin subunit alpha
P68871	HBB_HUMAN	Homo sapiens	Hemoglobin subunit beta