PDB 5u5t

PDB Links
Overview

PDB Information

PDB	5U5T
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli K-12
Gene Source	Homo sapiens
Primary Citation	Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase. Lingel, A., Sendzik, M., Huang, Y., Shultz, M.D., Cantwell, J., Dillon, M.P., Fu, X., Fuller, J., Gabriel, T., Gu, J., Jiang, X., Li, L., Liang, F., McKenna, M., Qi, W., Rao, W., Sheng, X., Shu, W., Sutton, J., Taft, B., Wang, L., Zeng, J., Zhang, H., Zhang, M., Zhao, K., Lindvall, M., Bussiere, D.E. J. Med. Chem.
Header	Transcription/Transferase
Released	2016-12-07
Resolution	1.600
CATH Insert Date	07 May, 2017

PDB Images (7)

Image of CATH 5u5t

5u5t

PDB 5u5t

Image of CATH 5u5tA

5u5tA

PDB Chain 5u5tA

Image of CATH 5u5tB

5u5tB

PDB Chain 5u5tB

Image of CATH 5u5tC

5u5tC

PDB Chain 5u5tC

Image of CATH 5u5tD

5u5tD

PDB Chain 5u5tD

Image of CATH 5u5tA00

5u5tA00

CATH Domain 5u5tA00

Image of CATH 5u5tB00

5u5tB00

CATH Domain 5u5tB00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped
C	08 May, 2017	Rejected
D	08 May, 2017	Rejected

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5u5tA00	14 Dec, 2017	2.130.10.10	Assigned
5u5tB00	14 Dec, 2017	2.130.10.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O75530	EED_HUMAN	Homo sapiens	Polycomb protein EED
O75530	EED_HUMAN	Homo sapiens	Polycomb protein EED
Q15910	EZH2_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase EZH2
Q15910	EZH2_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase EZH2