PDB Information

PDB5U5K
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli K-12
Gene SourceHomo sapiens
Primary Citation
Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase.
Lingel, A., Sendzik, M., Huang, Y., Shultz, M.D., Cantwell, J., Dillon, M.P., Fu, X., Fuller, J., Gabriel, T., Gu, J., Jiang, X., Li, L., Liang, F., McKenna, M., Qi, W., Rao, W., Sheng, X., Shu, W., Sutton, J., Taft, B., Wang, L., Zeng, J., Zhang, H., Zhang, M., Zhao, K., Lindvall, M., Bussiere, D.E.
J. Med. Chem.
HeaderTranscription
Released2016-12-06
Resolution2.330
CATH Insert Date07 May, 2017

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5u5kA00 14 Dec, 2017 2.130.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O75530 EED_HUMAN Homo sapiens Polycomb protein EED