PDB 5u3i

PDB Links
Overview

PDB Information

PDB	5U3I
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. Metcalf, B., Chuang, C., Dufu, K., Patel, M.P., Silva-Garcia, A., Johnson, C., Lu, Q., Partridge, J.R., Patskovska, L., Patskovsky, Y., Almo, S.C., Jacobson, M.P., Hua, L., Xu, Q., Gwaltney, S.L., Yee, C., Harris, J., Morgan, B.P., James, J., Xu, D., Hutchaleelaha, A., Paulvannan, K., Oksenberg, D., Li, Z. ACS Med Chem Lett
Header	Oxygen Transport
Released	2016-12-02
Resolution	1.950
CATH Insert Date	07 May, 2017

PDB Images (9)

Image of CATH 5u3i

5u3i

PDB 5u3i

Image of CATH 5u3iA

5u3iA

PDB Chain 5u3iA

Image of CATH 5u3iB

5u3iB

PDB Chain 5u3iB

Image of CATH 5u3iC

5u3iC

PDB Chain 5u3iC

Image of CATH 5u3iD

5u3iD

PDB Chain 5u3iD

Image of CATH 5u3iA00

5u3iA00

CATH Domain 5u3iA00

Image of CATH 5u3iB00

5u3iB00

CATH Domain 5u3iB00

Image of CATH 5u3iC00

5u3iC00

CATH Domain 5u3iC00

Image of CATH 5u3iD00

5u3iD00

CATH Domain 5u3iD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped
C	08 May, 2017	Chopped
D	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5u3iA00	23 May, 2017	1.10.490.10	Assigned
5u3iB00	23 May, 2017	1.10.490.10	Assigned
5u3iC00	23 May, 2017	1.10.490.10	Assigned
5u3iD00	23 May, 2017	1.10.490.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P68871	HBB_HUMAN	Homo sapiens	Hemoglobin subunit beta
P69905	HBA_HUMAN	Homo sapiens	Hemoglobin subunit alpha
P69905	HBA_HUMAN	Homo sapiens	Hemoglobin subunit alpha
P68871	HBB_HUMAN	Homo sapiens	Hemoglobin subunit beta