PDB 5u2e

PDB Information

PDB5U2E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli 'BL21-Gold(DE3)pLysS AG'
Gene SourceHomo sapiens
Primary Citation
Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis.
Andrews, F.H., Singh, A.R., Joshi, S., Smith, C.A., Morales, G.A., Garlich, J.R., Durden, D.L., Kutateladze, T.G.
Proc. Natl. Acad. Sci. U.S.A.
HeaderTranscription Regulator/Inhibitor
Released2016-11-30
Resolution1.990
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5u2eA01 23 May, 2017 1.20.920.10 Assigned
5u2eB01 23 May, 2017 1.20.920.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4