PDB 5tzw

PDB Links
Overview

PDB Information

PDB	5TZW
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders. Gomez, L., Massari, M.E., Vickers, T., Freestone, G., Vernier, W., Ly, K., Xu, R., McCarrick, M., Marrone, T., Metz, M., Yan, Y.G., Yoder, Z.W., Lemus, R., Broadbent, N.J., Barido, R., Warren, N., Schmelzer, K., Neul, D., Lee, D., Andersen, C.B., Sebring, K., Aertgeerts, K., Zhou, X., Tabatabaei, A., Peters, M., Breitenbucher, J.G. J. Med. Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2016-11-22
Resolution	1.590
CATH Insert Date	07 May, 2017

PDB Images (9)

Image of CATH 5tzw

5tzw

PDB 5tzw

Image of CATH 5tzwA

5tzwA

PDB Chain 5tzwA

Image of CATH 5tzwB

5tzwB

PDB Chain 5tzwB

Image of CATH 5tzwC

5tzwC

PDB Chain 5tzwC

Image of CATH 5tzwD

5tzwD

PDB Chain 5tzwD

Image of CATH 5tzwA00

5tzwA00

CATH Domain 5tzwA00

Image of CATH 5tzwB00

5tzwB00

CATH Domain 5tzwB00

Image of CATH 5tzwC00

5tzwC00

CATH Domain 5tzwC00

Image of CATH 5tzwD00

5tzwD00

CATH Domain 5tzwD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped
C	08 May, 2017	Chopped
D	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5tzwA00	22 May, 2017	1.10.1300.10	Assigned
5tzwB00	22 May, 2017	1.10.1300.10	Assigned
5tzwC00	22 May, 2017	1.10.1300.10	Assigned
5tzwD00	22 May, 2017	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase