PDB 5twn

PDB Information

PDB5TWN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHepatitis C virus genotype 1b (isolate Con1)
Primary Citation
The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase.
Eastman, K.J., Parcella, K., Yeung, K.S., Grant-Young, K.A., Zhu, J., Wang, T., Zhang, Z., Yin, Z., Beno, B.R., Sheriff, S., Kish, K., Tredup, J., Jardel, A.G., Halan, V., Ghosh, K., Parker, D., Mosure, K., Fang, H., Wang, Y.K., Lemm, J., Zhuo, X., Hanumegowda, U., Rigat, K., Donoso, M., Tuttle, M., Zvyaga, T., Haarhoff, Z., Meanwell, N.A., Soars, M.G., Roberts, S.B., Kadow, J.F.
Medchemcomm
HeaderTransferase/Transferase Inhibitor
Released2016-11-14
Resolution3.040
CATH Insert Date07 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5twnA01 22 May, 2017 Holding pen
5twnA02 22 May, 2017 Holding pen
5twnB01 22 May, 2017 Holding pen
5twnB02 22 May, 2017 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9WMX2 POLG_HCVCO Hepatitis C virus (isolate Con1) Genome polyprotein
Q9WMX2 POLG_HCVCO Hepatitis C virus (isolate Con1) Genome polyprotein