PDB 5twm

PDB Information

PDB5TWM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus genotype 2a (isolate JFH-1)
Primary Citation
The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase.
Eastman, K.J., Parcella, K., Yeung, K.S., Grant-Young, K.A., Zhu, J., Wang, T., Zhang, Z., Yin, Z., Beno, B.R., Sheriff, S., Kish, K., Tredup, J., Jardel, A.G., Halan, V., Ghosh, K., Parker, D., Mosure, K., Fang, H., Wang, Y.K., Lemm, J., Zhuo, X., Hanumegowda, U., Rigat, K., Donoso, M., Tuttle, M., Zvyaga, T., Haarhoff, Z., Meanwell, N.A., Soars, M.G., Roberts, S.B., Kadow, J.F.
Medchemcomm
HeaderTransferase/Transferase Inhibitor
Released2016-11-14
Resolution1.970
CATH Insert Date07 May, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5twmA01 22 May, 2017 Holding pen
5twmA02 22 May, 2017 Holding pen

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q99IB8 POLG_HCVJF Hepatitis C virus JFH-1 Genome polyprotein