Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans.
Thorarensen, A., Dowty, M.E., Banker, M.E., Juba, B., Jussif, J., Lin, T., Vincent, F., Czerwinski, R.M., Casimiro-Garcia, A., Unwalla, R., Trujillo, J.I., Liang, S., Balbo, P., Che, Y., Gilbert, A.M., Brown, M.F., Hayward, M., Montgomery, J., Leung, L., Yang, X., Soucy, S., Hegen, M., Coe, J., Langille, J., Vajdos, F., Chrencik, J., Telliez, J.B.
J. Med. Chem.