PDB 5tq4

PDB Information

PDB5TQ4
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin.
Jones, P., Storer, R.I., Sabnis, Y.A., Wakenhut, F.M., Whitlock, G.A., England, K.S., Mukaiyama, T., Dehnhardt, C.M., Coe, J.W., Kortum, S.W., Chrencik, J.E., Brown, D.G., Jones, R.M., Murphy, J.R., Yeoh, T., Morgan, P., Kilty, I.
J. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-10-23
Resolution2.300
CATH Insert Date07 May, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5tq4A01 22 May, 2017 3.30.200.20 Assigned
5tq4A02 22 May, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2
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