PDB 5tp9

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB Links
Overview

PDB Information

PDB	5TP9
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. Villemure, E., Volgraf, M., Jiang, Y., Wu, G., Ly, C.Q., Yuen, P.W., Lu, A., Luo, X., Liu, M., Zhang, S., Lupardus, P.J., Wallweber, H.J., Liederer, B.M., Deshmukh, G., Plise, E., Tay, S., Wang, T.M., Hanson, J.E., Hackos, D.H., Scearce-Levie, K., Schwarz, J.B., Sellers, B.D. ACS Med Chem Lett
Header	Transport Protein
Released	2016-10-20
Resolution	2.400
CATH Insert Date	04 Dec, 2016

PDB Images (7)

Image of CATH 5tp9

5tp9

PDB 5tp9

Image of CATH 5tp9A

5tp9A

PDB Chain 5tp9A

Image of CATH 5tp9B

5tp9B

PDB Chain 5tp9B

Image of CATH 5tp9A01

5tp9A01

CATH Domain 5tp9A01

Image of CATH 5tp9A02

5tp9A02

CATH Domain 5tp9A02

Image of CATH 5tp9B01

5tp9B01

CATH Domain 5tp9B01

Image of CATH 5tp9B02

5tp9B02

CATH Domain 5tp9B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Dec, 2016	Chopped
B	05 Dec, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5tp9A01	10 Dec, 2016	3.40.190.10	Assigned
5tp9A02	10 Dec, 2016	3.40.190.10	Assigned
5tp9B01	10 Dec, 2016	3.40.190.10	Assigned
5tp9B02	10 Dec, 2016	3.40.190.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q12879	NMDE1_HUMAN	Homo sapiens	Glutamate receptor ionotropic, NMDA 2A
Q05586	NMDZ1_HUMAN	Homo sapiens	Glutamate receptor ionotropic, NMDA 1