PDB 5tol

PDB Information

PDB5TOL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of furo[2,3-d][1,3]thiazinamines as beta amyloid cleaving enzyme-1 (BACE1) inhibitors.
Wu, Y.J., Guernon, J., Rajamani, R., Toyn, J.H., Ahlijanian, M.K., Albright, C.F., Muckelbauer, J., Chang, C., Camac, D., Macor, J.E., Thompson, L.A.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2016-10-18
Resolution2.510
CATH Insert Date04 Dec, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Dec, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5tolA01 10 Dec, 2016 2.40.70.10 Assigned
5tolA02 10 Dec, 2016 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1