PDB 5tkd

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PDB Links
Overview

PDB Information

PDB	5TKD
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Identification of imidazo[1,2-b]pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling. Moslin, R., Gardner, D., Santella, J., Zhang, Y., Duncia, J.V., Liu, C., Lin, J., Tokarski, J.S., Strnad, J., Pedicord, D., Chen, J., Blat, Y., Zupa-Fernandez, A., Cheng, L., Sun, H., Chaudhry, C., Huang, C., D'Arienzo, C., Sack, J.S., Muckelbauer, J.K., Chang, C., Tredup, J., Xie, D., Aranibar, N., Burke, J.R., Carter, P.H., Weinstein, D.S. Medchemcomm
Header	Transferase
Released	2016-10-06
Resolution	1.920
CATH Insert Date	08 Jan, 2017

PDB Images (7)

Image of CATH 5tkd

5tkd

PDB 5tkd

Image of CATH 5tkdA

5tkdA

PDB Chain 5tkdA

Image of CATH 5tkdB

5tkdB

PDB Chain 5tkdB

Image of CATH 5tkdA01

5tkdA01

CATH Domain 5tkdA01

Image of CATH 5tkdA02

5tkdA02

CATH Domain 5tkdA02

Image of CATH 5tkdB01

5tkdB01

CATH Domain 5tkdB01

Image of CATH 5tkdB02

5tkdB02

CATH Domain 5tkdB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	09 Jan, 2017	Chopped
B	09 Jan, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5tkdA01	20 Jan, 2017	3.30.200.20	Assigned
5tkdA02	20 Jan, 2017	1.10.510.10	Assigned
5tkdB01	20 Jan, 2017	3.30.200.20	Assigned
5tkdB02	20 Jan, 2017	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P29597	TYK2_HUMAN	Homo sapiens	Non-receptor tyrosine-protein kinase TYK2
P29597	TYK2_HUMAN	Homo sapiens	Non-receptor tyrosine-protein kinase TYK2