PDB Information

PDB5TH7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase.
Butler, K.V., Ma, A., Yu, W., Li, F., Tempel, W., Babault, N., Pittella-Silva, F., Shao, J., Wang, J., Luo, M., Vedadi, M., Brown, P.J., Arrowsmith, C.H., Jin, J.
J. Med. Chem.
HeaderTransferase
Released2016-09-29
Resolution1.950
CATH Insert Date20 Nov, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped
B 21 Nov, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5th7A00 16 Feb, 2017 2.170.270.10 Assigned
5th7B00 16 Feb, 2017 2.170.270.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9NQR1 KMT5A_HUMAN Homo sapiens N-lysine methyltransferase KMT5A
Q9NQR1 KMT5A_HUMAN Homo sapiens N-lysine methyltransferase KMT5A