PDB 5tgk

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Overview

PDB Information

PDB	5TGK
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli 'BL21-Gold(DE3)pLysS AG'
Gene Source	Homo sapiens
Primary Citation	Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator. Wang, C., Aleksandrov, A.A., Yang, Z., Forouhar, F., Proctor, E.A., Kota, P., An, J., Kaplan, A., Khazanov, N., Boel, G., Stockwell, B.R., Senderowitz, H., Dokholyan, N.V., Riordan, J.R., Brouillette, C.G., Hunt, J.F. J. Biol. Chem.
Header	Hydrolase
Released	2016-09-28
Resolution	1.910
CATH Insert Date	03 Jun, 2018

PDB Images (3)

Image of CATH 5tgk

5tgk

PDB 5tgk

Image of CATH 5tgkA

5tgkA

PDB Chain 5tgkA

Image of CATH 5tgkA00

5tgkA00

CATH Domain 5tgkA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	03 Jun, 2018	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5tgkA00	28 Jun, 2018	3.40.50.300	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P13569	CFTR_HUMAN	Homo sapiens	Cystic fibrosis transmembrane conductance regulator