PDB 5tcg

PDB Links
Overview

PDB Information

PDB	5TCG
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Primary Citation	A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase. Wellington, S., Nag, P.P., Michalska, K., Johnston, S.E., Jedrzejczak, R.P., Kaushik, V.K., Clatworthy, A.E., Siddiqi, N., McCarren, P., Bajrami, B., Maltseva, N.I., Combs, S., Fisher, S.L., Joachimiak, A., Schreiber, S.L., Hung, D.T. Nat. Chem. Biol.
Header	Lyase
Released	2016-09-15
Resolution	2.400
CATH Insert Date	14 Nov, 2017

PDB Images (21)

5tcg

PDB 5tcg

5tcgA

PDB Chain 5tcgA

5tcgB

PDB Chain 5tcgB

5tcgC

PDB Chain 5tcgC

5tcgD

PDB Chain 5tcgD

5tcgE

PDB Chain 5tcgE

5tcgF

PDB Chain 5tcgF

5tcgG

PDB Chain 5tcgG

5tcgH

PDB Chain 5tcgH

5tcgA00

CATH Domain 5tcgA00

5tcgB01

CATH Domain 5tcgB01

5tcgB02

CATH Domain 5tcgB02

5tcgC00

CATH Domain 5tcgC00

5tcgD01

CATH Domain 5tcgD01

5tcgD02

CATH Domain 5tcgD02

5tcgE00

CATH Domain 5tcgE00

5tcgF01

CATH Domain 5tcgF01

5tcgF02

CATH Domain 5tcgF02

5tcgG00

CATH Domain 5tcgG00

5tcgH01

CATH Domain 5tcgH01

5tcgH02

CATH Domain 5tcgH02

PDB Prints

PDB Chains (8)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped
C	14 Nov, 2017	Chopped
D	14 Nov, 2017	Chopped
E	14 Nov, 2017	Chopped
F	14 Nov, 2017	Chopped
G	14 Nov, 2017	Chopped
H	14 Nov, 2017	Chopped

CATH Domains (12)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5tcgA00	10 Dec, 2017	3.20.20.70	Assigned
5tcgB01	10 Dec, 2017	3.40.50.1100	Assigned
5tcgB02	10 Dec, 2017	3.40.50.1100	Assigned
5tcgC00	10 Dec, 2017	3.20.20.70	Assigned
5tcgD01	10 Dec, 2017	3.40.50.1100	Assigned
5tcgD02	10 Dec, 2017	3.40.50.1100	Assigned
5tcgE00	10 Dec, 2017	3.20.20.70	Assigned
5tcgF01	10 Dec, 2017	3.40.50.1100	Assigned
5tcgF02	10 Dec, 2017	3.40.50.1100	Assigned
5tcgG00	10 Dec, 2017	3.20.20.70	Assigned
5tcgH01	10 Dec, 2017	3.40.50.1100	Assigned
5tcgH02	10 Dec, 2017	3.40.50.1100	Assigned

UniProtKB Entries (8)

Accession	Gene ID	Taxon	Description
P9WFY1	TRPA_MYCTU	Mycobacterium tuberculosis H37Rv	Tryptophan synthase alpha chain
P9WFX9	TRPB_MYCTU	Mycobacterium tuberculosis H37Rv	Tryptophan synthase beta chain
P9WFX9	TRPB_MYCTU	Mycobacterium tuberculosis H37Rv	Tryptophan synthase beta chain
P9WFY1	TRPA_MYCTU	Mycobacterium tuberculosis H37Rv	Tryptophan synthase alpha chain
P9WFX9	TRPB_MYCTU	Mycobacterium tuberculosis H37Rv	Tryptophan synthase beta chain
P9WFY1	TRPA_MYCTU	Mycobacterium tuberculosis H37Rv	Tryptophan synthase alpha chain
P9WFX9	TRPB_MYCTU	Mycobacterium tuberculosis H37Rv	Tryptophan synthase beta chain
P9WFY1	TRPA_MYCTU	Mycobacterium tuberculosis H37Rv	Tryptophan synthase alpha chain