PDB 5tca

PDB Information

PDB5TCA
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors.
Yang, C.Y., Phillips, J.G., Stuckey, J.A., Bai, L., Sun, H., Delproposto, J., Brown, W.C., Chinnaswamy, K.
ACS Med Chem Lett
HeaderHydrolase/Hydrolase Inhibitor
Released2016-09-14
Resolution3.150
CATH Insert Date30 Oct, 2016

PDB Images (22)

PDB Prints

PDB Chains (7)

Chain ID Date inserted into CATH CATH Status
A 31 Oct, 2016 Chopped
B 31 Oct, 2016 Chopped
C 31 Oct, 2016 Chopped
D 31 Oct, 2016 Chopped
E 31 Oct, 2016 Chopped
F 31 Oct, 2016 Chopped
G 31 Oct, 2016 Chopped

CATH Domains (14)

Domain ID Date inserted into CATH Superfamily CATH Status
5tcaA01 03 Nov, 2016 2.40.10.10 Assigned
5tcaA02 03 Nov, 2016 2.40.10.10 Assigned
5tcaB01 03 Nov, 2016 2.40.10.10 Assigned
5tcaB02 03 Nov, 2016 2.40.10.10 Assigned
5tcaC01 03 Nov, 2016 2.40.10.10 Assigned
5tcaC02 03 Nov, 2016 2.40.10.10 Assigned
5tcaD01 03 Nov, 2016 2.40.10.10 Assigned
5tcaD02 03 Nov, 2016 2.40.10.10 Assigned
5tcaE01 03 Nov, 2016 2.40.10.10 Assigned
5tcaE02 03 Nov, 2016 2.40.10.10 Assigned
5tcaF01 03 Nov, 2016 2.40.10.10 Assigned
5tcaF02 03 Nov, 2016 2.40.10.10 Assigned
5tcaG01 03 Nov, 2016 2.40.10.10 Assigned
5tcaG02 03 Nov, 2016 2.40.10.10 Assigned

UniProtKB Entries (7)

Accession Gene ID Taxon Description
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D