PDB 5tbm

PDB Information

PDB5TBM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A Small-Molecule Antagonist of HIF2 alpha Is Efficacious in Preclinical Models of Renal Cell Carcinoma.
Wallace, E.M., Rizzi, J.P., Han, G., Wehn, P.M., Cao, Z., Du, X., Cheng, T., Czerwinski, R.M., Dixon, D.D., Goggin, B.S., Grina, J.A., Halfmann, M.M., Maddie, M.A., Olive, S.R., Schlachter, S.T., Tan, H., Wang, B., Wang, K., Xie, S., Xu, R., Yang, H., Josey, J.A.
Cancer Res.
HeaderTranscription
Released2016-09-12
Resolution1.850
CATH Insert Date09 Oct, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Oct, 2016 Chopped
B 10 Oct, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5tbmA00 14 Oct, 2016 3.30.450.20 Assigned
5tbmB01 14 Oct, 2016 3.30.450.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27540 ARNT_HUMAN Homo sapiens Aryl hydrocarbon receptor nuclear translocator
Q99814 EPAS1_HUMAN Homo sapiens Endothelial PAS domain-containing protein 1