PDB Information

PDB5TBH
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceMus musculus
Primary Citation
Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors.
Halby, L., Marechal, N., Pechalrieu, D., Cura, V., Franchini, D.M., Faux, C., Alby, F., Troffer-Charlier, N., Kudithipudi, S., Jeltsch, A., Aouadi, W., Decroly, E., Guillemot, J.C., Page, P., Ferroud, C., Bonnefond, L., Guianvarc'h, D., Cavarelli, J., Arimondo, P.B.
Philos.Trans.R.Soc.Lond.B Biol.Sci.
HeaderTransferase
Released2016-09-12
Resolution2.340
CATH Insert Date14 Nov, 2017

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5tbhA01 16 Dec, 2017 3.40.50.150 Assigned
5tbhA02 16 Dec, 2017 2.70.160.11 Assigned
5tbhB01 16 Dec, 2017 3.40.50.150 Assigned
5tbhB02 16 Dec, 2017 2.70.160.11 Assigned
5tbhC01 16 Dec, 2017 3.40.50.150 Assigned
5tbhC02 16 Dec, 2017 2.70.160.11 Assigned
5tbhD01 16 Dec, 2017 3.40.50.150 Assigned
5tbhD02 16 Dec, 2017 2.70.160.11 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9WVG6 CARM1_MOUSE Mus musculus Histone-arginine methyltransferase CARM1
Q9WVG6 CARM1_MOUSE Mus musculus Histone-arginine methyltransferase CARM1
Q9WVG6 CARM1_MOUSE Mus musculus Histone-arginine methyltransferase CARM1
Q9WVG6 CARM1_MOUSE Mus musculus Histone-arginine methyltransferase CARM1